Astellas Pharmaceuticals manufactures and markets Protopic to treat an allergic reaction that causes skin inflammation called eczema. The FDA approved Protopic in December 2000. Unfortunately, Protopic is linked to severe and fatal side effects, including skin cancer and lymphoma.

Protopic Side Effects: Skin Cancer

Skin cancer is a serious side effect of Protopic. Skin cancer is a severe and progressively worsening growth on the skin. Skin cancer usually develops on the skin’s outermost layer, so the tumor is clearly visible. Therefore, skin cancer is typically detected early and is non-fatal. Skin cancer symptoms include:

  • Small lumps that are shiny, waxy, pale, and smooth
  • Red lumps that are firm
  • Bleeding or crusty sores
  • Rough skin patches

Protopic Side Effects: Lymphoma Cancers

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Lymphoma cancer is a severe Protopic side effect. Lymphoma is a cancer group that is  medically classified as a hematological malignancy, meaning it arises from the blood (specifically the white blood cells). Lymphoma’s most common symptom is enlarged, swelling of the lymph nodes in the neck, underarm, or groin. Other Lymphoma cancer symptoms may include:

  • Unexplained fever, weight loss, or poor appetite
  • Constant fatigue
  • Itchy skin
  • Reddened, thick, or dark patches on the skin

Protopic linked to Cancer Side Effects

In March 2005, the FDA issued a Public Health Advisory announcing that animal studies linked Protopic to skin cancer and lymphoma. The animal studies revealed that three different animal species, mice, rats, and monkeys, developed cancerous side effects after exposure to Protopic. The studies also concluded that the cancer side effect risk increased with higher doses and longer duration. The FDA also announced that it received a few reports from patients that developed cancer after using Protopic.

FDA Protopic Side Effects Warning

In January 2006, the FDA ordered Astellas Pharmaceuticals, Protopic’s manufacturer, to add a black box warning to Protopic’s label stating:

  • Protopic should only be used if all other therapy fails
  • To avoid Protopic use in children under two years old
  • Only to use Protopic for short periods of time and not continuously
  • To use the smallest Protopic dose needed to control the patient’s symptoms

Injured by Protopic Side Effects

If you or a loved one has been injured by Protopic’s side effects, please contact us today as you may be entitled to compensation.

Published November 17, 2011 by