Were you diagnosed with kidney failure or other kidney problems following treatment with Nexium, Prilosec and Prevacid?

Recent studies suggest that patients who use proton pump inhibitors for a long period of time may be more likely to develop serious kidney side effects, including:

  • Acute Interstitial Nephritis
  • Acute Kidney Injury
  • Chronic Kidney Disease
  • Kidney (renal) Failure

Hundreds of Nexium, Prilosec and Prevacid lawsuit plaintiffs have accused drug companies of concealing the risks associated with these popular heartburn medications. You may be eligible to file a lawsuit of your own if you or a loved one developed kidney problems that may be associated with their use.

The nationwide law firm of Bernstein Liebhard LLP is offering free, no-obligation case reviews to individuals who may have been injured by prescription or over-the-counter versions of Nexium, Prilosec or Prevacid. To contact an experienced attorney today, please call 1-877-779-1414.

What are Proton Pump Inhibitors?

Nexium, Prilosec and Prevacid belong to a class of medications called proton pump inhibitors, which are indicated to treat conditions associated with the excess production of stomach acid, including:

  • Gastroesophageal reflux disease (GERD)
  • Heartburn
  • Acid indigestion
  • Damage to the lining of the esophagus
  • Ulcers
  • Stomach infections

Over-the-counter versions of these drugs include:

  • Nexium 24HR
  • Prilosec OTC
  • Prevacid 24HR

Other proton pump inhibitors include:

  • Protonix
  • Aciphex
  • Kapidex and Dexilant

Are Proton Pump Inhibitors Overused?

Drugs like Nexium, Prilosec, and Prevacid have been aggressively marketed by their manufacturers.  Because of these efforts, proton pump inhibitors are prescribed to 15 million Americans every year. Nexium was ranked as the fourth most-popular drug in the U.S. from April 2014 through March 2015.

This popularity is concerning, however, as some studies have suggested that proton pump inhibitors are frequently overused and misused.

In 2016, for example, research published in JAMA Internal Medicine suggested that up to 70% of proton pump inhibitor prescriptions are inappropriate. The same study found that a quarter of all long-term users could stop taking the medications without an increase or recurrence of their heartburn symptoms.

Australian researchers writing in the September 2017 issue of the  Journal of Clinical Pharmacy and Therapeutics also suggested that the drugs are overused worldwide and recommended that proton pump inhibitors become the focus of deprescribing programs.

Proton Pump Inhibitor Side Effects

Because they have become so commonplace, many patients believe that drugs like Nexium, Prilosec, and Prevacid can be taken without risk. However, that is not the case, as a growing body of research has linked their use to a range of serious side effects, including:

  • Heart Attack
  • Bone Fractures/osteoporosis
  • Dementia
  • Clostridium difficile (C. diff.) infection
  • B12 deficiency
  • Hypomagnesemia (Low Magnesium)
  • Chronic Inflammation of the Stomach
  • Kidney Failure and other renal problems

Long-term Use of Nexium, Prilosec and Prevacid May Harm the Kidneys

In December 2015, the U.S. Food & Drug Administration (FDA) ordered all proton pump inhibitor manufacturers to modify the drugs’ prescribing information to note acute interstitial nephritis as a possible side effect.

Acute interstitial nephritis is a serious hypersensitivity condition that causes the kidney tubules to become inflamed. Untreated, it can lead to chronic kidney disease and kidney failure.

The FDA only acted after it was sued by the consumer advocacy group Public Citizen.

No other kidney side effects are listed on proton pump inhibitor labels, despite a growing body of evidence suggesting that these medications may also be associated with an increased risk of kidney failure, chronic kidney disease, and acute kidney injury.

In April 2015, for example, research published in CMAJ Open suggested that long-term proton pump inhibitor use tripled the risk of nephritis and increased the risk of acute kidney injury 2.5-fold.

A January 2016 study published in JAMA Internal Medicine found a 20-50% increased risk of Chronic Kidney Disease (CKD) in people who took proton pump inhibitors for an extended period. Those who used the medications twice a day were 46% more likely to develop chronic kidney disease, while once-daily users had a 15% higher risk.

In April 2016, the Journal of the American Society of Nephrology  published a paper linking long-term use of proton pump inhibitors to a 96% increased risk of kidney failure and a 26% increased risk of chronic kidney disease.

Nexium, Prilosec and Prevacid Lawsuits Mount in U.S. Courts

As evidence of their kidney side effects has accumulated, a growing number of plaintiffs have taken legal action against the manufacturers of Nexium, Prilosec and Prevacid, as well as other proton pump inhibitors.

Plaintiffs pursuing Nexium, Prilosec and Prevacid lawsuits claim that the drug’s makers have been aware of reports linking proton pump inhibitors to kidney injuries for decades. Yet they have failed to take adequate measures to provide doctors and patients with appropriate safety warnings.

On August 2, 2017, the U.S. Judicial Panel on Multidistrict Litigation centralized all federally-filed proton pump inhibitor lawsuits involving kidney failure, chronic kidney disease, and other kidney injuries in the U.S. District Court, District of New Jersey. The specific drugs at issue in this litigation include Nexium, Prilosec, Prevacid, Dexilant, and Protonix.

Initially, 166 proton pump inhibitor lawsuits were transferred to the District of New Jersey. But by October 2017, more than 270 cases were pending in the proceeding. Legal experts believe that the kidney injury litigation involving Nexium, Prilosec and Prevacid could ultimately include hundreds – if not thousands – of lawsuits.

Contact a Proton Pump Inhibitor Lawyer Today

People who have been diagnosed with kidney failure or other kidney complications following treatment with Nexium, Prilosec or Prevacid may be entitled to compensation for.

  • Medical Bills
  • Lost Wages
  • Pain & Suffering
  • Emotional Distress
  • Wrongful Death
  • More

Our experienced proton pump inhibitor lawyers will evaluate your case for free and fully explain all of your legal rights and options. To learn more about filing a Nexium, Prilosec, or Prevacid lawsuit, please call our office as soon as possible at 1-877-779-1414.

Published October 16, 2017 by