Bernstein Liebhard LLP, a New York law firm nationally recognized for its consumer protection and mass tort practices, reports on a June 11, 2012 study that found that diabetes medications such as Actos may cause a serious eye problem called diabetic macular edema. The study, published in the Archives of Internal Medicine, found that patients who took Actos or other thiazolidinedione drugs had a two to three fold increased risk of developing diabetic macular edema, a condition that can lead to blindness. Researchers collected data on more than 100,000 people with type 2 diabetes from the British Health Improvement Network database. After one year, 1.3 percent of patients taking thiazolidinedione developed the eye problem, compared to 0.2 percent of patients who did not take the drugs. Macular edema is a swelling of the part of the eye responsible for sharp vision when looking straight ahead. The swelling occurs when fluid leaks into the center of the macula and blurs vision.

Lead researcher Dr. Iskandar Idris, an associate professor in diabetes medicine at the University of Nottingham, told HealthDay: “More aggressive management of risk factors for macular edema should be implemented in patients who take thiazolidinedione. In addition, routine screening for visual acuity should be performed during routine diabetes review, especially for patients who take thiazolidinediones.” Drugs in this category include Avandia and Actos.

Other Actos Side Effects Include Bladder Cancer

This latest study adds to prior concerns about other Actos side effects, such as an increased risk of developing bladder cancer. A May 31, 2012 study published in the British Medical Journal found that patients who took Actos had an 83 percent increased rate of developing bladder cancer, which increased to 88 percent for those who took Actos for two years or longer—or those who consumed 28,000 milligrams or more. In May 2011, the U.S. Food and Drug Administration (“FDA”) published a study, which concluded that there is a link between Actos and bladder cancer; the FDA added a warning label to alert users about Actos side effects. While Actos is still available in the United States, it has been recalled in both Germany and France.

The lawyers at Bernstein Liebhard LLP are evaluating potential lawsuits against the drug manufacturer, Takeda Pharmaceuticals, on behalf of individuals who experienced Actos side effects such as bladder cancer and diabetic macular edema. Those who experienced Actos side effects may be entitled to compensation for medical expenses, lost wages, pain and suffering and other injuries. For more information about bringing an Actos lawsuit, visit

About Bernstein Liebhard LLP

Bernstein Liebhard LLP is a New York-based law firm exclusively representing injured persons in complex individual and class action lawsuits nationwide since 1993, including those who have been harmed by dangerous drugs, defective medical devices and consumer products. The firm has been named by The National Law Journal to the “Plaintiffs’ Hot List,” recognizing the top plaintiffs’ firms in the country, for the past nine consecutive years. Only two firms in the country have been selected for the Hot List nine years in a row.

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Published June 14, 2012 by